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PED-EM-L  August 2009

PED-EM-L August 2009

Subject:

Re: hylenex

From:

don zweig <[log in to unmask]>

Reply-To:

don zweig <[log in to unmask]>

Date:

Wed, 19 Aug 2009 10:58:11 -0700

Content-Type:

text/plain

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Parts/Attachments

text/plain (128 lines)

what is hylenex?
On Aug 19, 2009, at 10:07 AM, Jason Foland wrote:

> This is very interesting. Can someone forward me some articles,  
> references, and/ or protocols so I can look at the possibility of  
> using this at our institution.
>
>
>
> Jason
>
>
>
>
> Jason A. Foland, MD
> Pediatric Critical Care Physician
> Nemours Children's Clinic
> www.nemours.org
> Medical Director, Pediatric Respiratory Therapy
> Sacred Heart Women & Children's Hospital
> www.sacred-heart.org
> Pensacola, Florida
> [log in to unmask]
>
>
>
>
>
>> Date: Wed, 19 Aug 2009 10:39:35 -0500
>> From: [log in to unmask]
>> Subject: Re: hylenex
>> To: [log in to unmask]
>>
>> How about Amphadase? It is cheaper.
>> Bovine vs Hamster...
>> Any comments?
>>
>>
>> -----Original Message-----
>> From: Pediatric Emergency Medicine Discussion List
>> [mailto:[log in to unmask]] On Behalf Of Peter Antevy
>> Sent: Tuesday, August 18, 2009 12:08 PM
>> To: [log in to unmask]
>> Subject: Re: hylenex
>>
>> Bob, we've created a hylenex protocol and have started using it in  
>> our
>> ED. It's simple and easy and a great alternative to have. You can
>> infuse the usual 20 per kg NS bolus rapidly just the same as via IV.
>> Also it takes 3 minutes and one person to start rather than 2-3  
>> nurses
>> and 30 minutes.
>>
>> Peter
>>
>> -----Original Message-----
>>
>> From: BOB BELFER <[log in to unmask]>
>> Subj: hylenex
>> Date: Tue Aug 18, 2009 12:28 pm
>> Size: 1K
>> To: [log in to unmask]
>>
>> Anyone with any experience with below?
>> thanks,
>>
>>
>>
>> Bob Belfer
>>
>>
>>
>>
>> Clinical Trial*
>> INFUSE-Pediatric Rehydration Study: Phase IV Study of Subcutaneous
>> Rehydration With Recombinant Human Hyaluronidase (hylenex  
>> recombinant)
>> for Infants and Children
>> Purpose: The aim of the study is to evaluate the safety,  
>> effectiveness
>> and ease of use of subcutaneous rehydration using hylenex
>> recombinant-augmented subcutaneous infusion of fluids and  
>> electrolytes
>> for the rehydration of pediatric patients with mild to moderate
>> dehydration.
>> Study Type: Interventional
>> Enrollment: 51
>>
>> Study Design: Treatment, non-randomized, open label, uncontrolled,
>> single group assignment, safety/efficacy study Primary Outcome  
>> Measures:
>>
>>
>> Rehydration success rate (effectiveness) in children treated with
>> hylenex recombinant-augmented fluid infusion
>> Secondary Outcome Measures:
>>
>>
>> Safety of hylenex recombinant-augmented fluid infusion in children
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>> the
>> message: info PED-EM-L
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