We just started using hylenex , context is that we are a small community Peds ED, Level 4, 16.5k kids/year. Single physician coverage, APC coverage 8-10hrs.
We utilize hylenex for moderate dehydration, explain to parents we will attempt IV x2, and if unsuccessful will move to SQ. Parents receptive and love it.
It works because we are small and can't support a PICC team ($$), are housed in an adult hospital so Peds Anesthesia not in house 24-7, and during RSV/Flu season it's not ideal to have NICU nurses help us (but in off season they do help us with difficult access cases).
Let me know if you want me to send policy.
Sent from my iPhone
> On Jun 9, 2017, at 16:18, Van der Jagt, Elise <[log in to unmask]> wrote:
> Hi, Sergey,
> You might want to contact Dr. Sharon Mace at the Cleveland Clinic. She is a friend of mine in pediatric emergency medicine and first introduced me again to the concept (I was familiar with it since it had been used in the 1950s and 60s, as well as in veterinary medicine). I believe she was involved in the clinical trials of Hylenex (hyaluronidase) which is used under the skin before the IV catheter is inserted. She was using it at the time, probably about 10 years ago and was very impressed with it. She used to be here in Rochester, then in Syracuse and then went out to the Cleveland Clinics. She is wonderful to work with and please give her my regards. I am also glad to contact her and give you an introduction, if that would work better.
> I personally have used clysis on one of our cats once when she couldn’t drink, and it worked well, was easy and kept the cat hydrated for at least 24-36 hours.
> Elise W. van der Jagt, MD, MPH, FAAP, FCP, SFHM,
> Professor of Pediatrics and Critical Care
> Chief, Pediatric Hospital Medicine
> University of Rochester Medical Center
> 601 Elmwood Ave., Box 667
> Rochester, NY 14642
> Tele: 585-275-8138/585-276-4113
> Fax: 585-276-1128
> Golisano Children's Hospital
> -----Original Message-----
> From: Pediatric Emergency Medicine Discussion List [mailto:[log in to unmask]] On Behalf Of Sergey Kunkov
> Sent: Friday, June 09, 2017 10:31 AM
> To: [log in to unmask]
> Subject: Clysis
> Dear colleagues,
> I wanted to ask you about clysis: I know there was a discussion a few years back about its use , but does anyone is using it on a routine basis or , better yet, incorporated it in some kind of a protocol for difficult IV access?
> Thank you very much
> Sergey Kunkov
> Stony Brook
> For more information, send mail to [log in to unmask] with the message: info PED-EM-L The URL for the PED-EM-L Web Page is:
> For more information, send mail to [log in to unmask] with the message: info PED-EM-L
> The URL for the PED-EM-L Web Page is:
For more information, send mail to [log in to unmask] with the message: info PED-EM-L
The URL for the PED-EM-L Web Page is: