Vijanto J: Disinfection of Surgical Wounds without Inhibition of Normal
Wound Healing. Arch Surg 1980; 115: 253. Appendectomy wounds sprayed with
5% povidone iodine had infx rates of 19% versus 8.5% in control group.
Those getting the dilute 1% p-i solution had infx rate of 2.6%. Also,
rabbit conjunctiva studies show marked injection and corneal ulcers
dependent upon concentration. Edlich (probably appropriately) admonishes
against putting anything into the wound that you wouldn't put into the eye.
I personally use dilute p-i (1%) when caring for high risk wounds. You
are correct in pointing out the paucity of data about this in ED wounds.
Carey Chisholm, MD
Methodist Hospital of Indiana
> Let me quibble for a moment with the assertion that iodine (as in
>Betadine Solution) is toxic to tissues. I have heard many surgeons express
>this as fact, but it is not, to my knowledge, substantiated by the
>A misreading of the studies I think has led to propagation of this myth ...
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