Is everyone using the same formula for LET? Can the different post-ers
(sp?!) on this topic present their formulas to the group?
On Tue, 13 Aug 1996, Michael Kim wrote:
> Hi Dan,
> Here at Children's Hospital of Wisconsin, we have been using
> LET(LAT:Lidocaine/Adrenaline/Tetracaine) for almost a year in conjunction
> with AC(Adrenaline/Cocaine) with great success. At first, there were some
> skepticism, but now almost all the minor lacerations of scalp and face
> are repaired with LAT. In the past, AC solution was supplied to our ED in a
> sterile plastic syringes and was applied on a guaze or by cotton swab.
> Then we began to mix them with methylcellulose to make a gel form by the
> ED nurses.This gel form was made by mixing the AC solution with
> Methylcellulose powder in a plastic cup which was not sterile. Although
> we have not sought the infection rate from the gel form, I do not recall
> any problems.
> LAT is exclusively used in gel form in our ED made under sterile
> conditions by pharmacy and supplied in 1.5 cc sterile plastic
> syringes. Since gel is the only form we use, it can be prepared in
> batches by pharmacy without worrying about pssible contamination during
> mixing in the ED as we have before with AC.
> The shelf life of this preparation appears to be approx. 3 weeks with
> antioxidant mixed in. After that it turns brown from Epinephrine
> oxidation. I do not understand how the shelf life is prolonged by using
> unsterile syringe.
> I feel why concern yourself with possible contamination when it can be
> made sterily and stored for a reasonable amount of time.
> Michael Kim
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