I don't have a reference available, but off the top of my head:
I don't think that RSV changes it major antigenic determinants. I would expect, were that
the case, that adults would continue to be susceptiple. There are, however, at least two
serotypes, so that infection with different serotypes in the same season can occur. I
think the different types have slightly different seasonal patterns.
The partial immunity referred to by Dr. Pershad explains the pattern of illness seen in
young children. RSV infections get less severe with age, and basically are not seen
over 3-4 years old. By this time, enough exposure for complete immunity has occurred.
Benjamin Braun MSIV
On Sat, 17 Jan 1998 18:09:39 -0600, Jay Pershad, M.D. wrote:
>I believe they can. I think it is like influenza virus and can change
>it's antigenic composition & reinfect.
> Can kids get RSV twice in the same year, i.e., they had it at 2
> months and have it again at 10 months? Can they get it twice
> The kids in our ED with respiratory complaints are running about
> 85% positive for RSV.
> Martin Oliver, PA-C
> Capo Beach, CA
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