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As I review my Sanford about this issue, there is a citation from
Clinical Infectious Diseases, Vol. 19, 1994 about this very issue. IM
Benzathine PCN reportedly decreased the rate of ARF from 2.8 to 0.2%. I
have not seen the original article, but these numbers are what many
people seem to be looking for. As others have pointed out, prevention
of ARF was associated with clearance of GABHS from the pharynx.
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