Mick asked about a high incidence of wound infections with Dermabond. We have not seen many
infections at our institution in Canada where it has been used for about 4 years. A study you may
want to pull looked at the "Comparison of effects of suture and cyanoacrylate tissue adhesive on
bacterial counts in contaminated lacerations" (Antimicrobial agents and chemotherapy, 1995; 2:
559-560). This was a small study done on guinea pigs that showed tissue adhesive to be
bacteriostatic against S. aureus.
Other than this study I have not seen any literature on the incidence of wound infections
comparing suture to adhesive.
j. m. connors wrote:
> Have folks been seeing a high incidence of wound infections with
> Dermabond?? We had none despite a significant amount of usages, until
> last weekend when we had 3. I have heard that Dr. Trott at Cincinnati
> and the author of the text on wounds and lacerations has stopped using
> Dermabond because of increased infection rates. He feels its related to
> the bacteria being trapped under the glue rather than the poor wound
> care which has been hypothesized by others. Thoughts??
> Mick Connors
> Knoxville, TN
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