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We are also interested in creating a "difficult stick" protocol using hyaluronidase. From my understanding the benefit of Hylenex is that it is less likely to cause allergic reactions because it is human recombinant. My pharmacy would prefer to use a less expensive nonhuman form. They have extensive experience and use in the hospice population and haven't seen the reported 9% reaction rate. Anyone else have experience with nonhuman hyaluronidase to perform clysis?

Jason

Jason Foland, MD
Clinical Associate Professor of Pediatrics
Florida State University School of Medicine
Medical Director of Pediatric Respiratory Care
Pediatric ICU
Sacred Heart Children's Hospital
Pensacola, Florida

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On 2012-02-12 21:25:07 +0000 Dominic Lucia <[log in to unmask]> wrote:

> 
> Hello all,
> I have been informed Hylenex is back on the market with FDA approval for 
> use and my institution will be carrying it. Does anyone have experience using 
> this with children in the ED for rehydration (and presumably difficult IV 
> access) ? 
>  
> It is something that I am not familiar with and wanted some front line 
> feedback on your experiences with it in children. Thanks in advance.
>  
> Dominic Lucia M.D.
> Medical Director Emergency Medicine
> Children's Hospital at Scott and White
> office: 254 724-1068
> [log in to unmask]
> 
> For more information, send mail to [log in to unmask] with the 
> message: info PED-EM-L
> The URL for the PED-EM-L Web Page is:
>                  http://listserv.brown.edu/ped-em-l.html
> 

For more information, send mail to [log in to unmask] with the message: info PED-EM-L
The URL for the PED-EM-L Web Page is:
                 http://listserv.brown.edu/ped-em-l.html