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I am also working on having intranasal ketamine available in our formulary. Does anyone have experience on MAX dose for intranasal dosing?




> On May 24, 2017, at 8:59 AM, Naveen Poonai <[log in to unmask]> wrote:
> 
> We completed a systematic review on this topic. Sedation is inconsistent.  Onset and duration of sedation are quite variable so child needs extended monitoring. Effective sedation for laceration repair is at least 9 mg/kg.
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> Naveen Poonai, Kyle Canton, Samina Ali, Shawn Hendrikx, Amit Shah, Michael Miller, Gary Joubert , Michael Rieder, Lisa Hartling. Intranasal ketamine for procedural sedation and analgesia in children: a systematic review. PLoS One. 2017; 12(3):e0173253. DOI: 10.1371/journal.pone.0173253. PMID 28319161
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> Naveen Poonai MSc MD FRCPC
> 
> Paediatric Emergency Physician, Children's Hospital, London Health Sciences Center
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> Associate Professor Paediatrics and Internal Medicine, Schulich School of Medicine & Dentistry
> 
> Associate Scientist, Child Health Research Institute
> 
> Research Director, Division of Paediatric Emergency Medicine
> 
> 800 Commissioners Road East, Room E4-221, London, Ontario, N6A 5W9
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> Phone: 519 694 5309  Fax: 519 667 6769 Alternate email: [log in to unmask]
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> ________________________________
> From: Pediatric Emergency Medicine Discussion List <[log in to unmask]> on behalf of Ali Ozcan <[log in to unmask]>
> Sent: Wednesday, May 24, 2017 1:09 AM
> To: [log in to unmask]
> Subject: Intranasal Ketamine
> 
> Hi All,
> We will start to use intranasal ketamine in our Pediatric Emergency for pain control and sedation. A couple of questions for the group:
> Is anyone using it for simple laceration repairs, if so what is your dose?
> What dose is usually adequate for 1. mild and 2. moderate sedation?
> How long does it take for patients to recover after IN ketamine when it is given for 1. mild and 2. moderate sedation?
> 
> Thanks for your help! I'm happy to share the responses with anyone who is interested.
> 
> 
> Ali Ozcan, PGY4
> Pediatric Emergency Medicine
> Beaumont Children's Hospital
> 
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For more information, send mail to [log in to unmask] with the message: info PED-EM-L
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