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Tom
Why was the trail at Vandy unsuccessful 

Sent from Jill C Obremskey's iPhone 

> On Jun 9, 2017, at 11:56 PM, Julian Orenstein <[log in to unmask]> wrote:
> 
> My father was a general practitioner from before World War II. He describes, in the aftermath of the liberation, serving as a physician for UNRRA (United Nations relief and rescue agency) going to displaced person camps. These camps were the same concentration camps that had just been liberated from the Germans. In the conditions of extreme starvation and emaciation that he encountered, one of the few tools he had at his disposal was providing fluids by clysis. So, as a resident in pediatrics, when I would tell him of the difficulties we sometimes had getting IVs into babies, he wondered why we had abandoned a well-known, simple, successful practice. These conversations took place in the mid-1980s, therefore, at least 15 years before the rediscovery of subcutaneous fluids.
> 
> I hope this walk down memory lane has been instructive and entertaining. Signed, grandpa Simpson. 
> 
> Julian Orenstein
> 
> 
>> On Jun 9, 2017, at 3:17 PM, Abramo, Thomas <[log in to unmask]> wrote:
>> 
>> the role of Clysis is an old method of hydration going way back but with incorporating Hylenex( Enzyme which breaks down the hyaluronidase subcutaneous  network)  it has become a great option for difficult or unobtainable IV access.  The drug is no being market in the  ophthalmology and cosmetic surgery field but is available to be utilized for IV rehydration. 
>> a multi-center PED study was ongoing for Hylenex as an alternative for rehydration but start due to certain issues. 
>> 
>> http://hylenex.com/mechanism-of-action/
>> 
>> there are mutli-centers that have protocols for using this agent for rehydration.
>> 
>> Thomas Abramo MD
>> Please excuse inadvertent errors due to the use of Dragon voice recognition software.
>>> Thanks,
>>> Thomas J. Abramo, M.D., FAAP, FACEP
>>> Professor of Pediatric and Emergency Medicine
>>> University of Arkansas School of Medicine
>>> Section Chief  Division of Pediatric Emergency Medicine
>>> Office 501-364 2299
>>> Confidentiality Notice: This information is peer review material designed to improve the quality of patient care and is privileged and confidential. This e-mail message, including any attachments, is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review, use, disclosure or distribution is prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message.
>> 
>> ________________________________________
>> From: Pediatric Emergency Medicine Discussion List <[log in to unmask]> on behalf of Sergey Kunkov <[log in to unmask]>
>> Sent: Friday, June 9, 2017 9:31 AM
>> To: [log in to unmask]
>> Subject: Clysis
>> 
>> Dear colleagues,
>> 
>> I wanted  to ask you about clysis: I know there was a discussion a few
>> years back about its use , but does anyone is using it on a routine basis
>> or , better yet, incorporated it in some kind of a protocol for difficult
>> IV access?
>> 
>> Thank you very much
>> 
>> Sergey Kunkov
>> Stony Brook
>> 
>> For more information, send mail to [log in to unmask] with the message: info PED-EM-L
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>> 
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> 
> For more information, send mail to [log in to unmask] with the message: info PED-EM-L
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For more information, send mail to [log in to unmask] with the message: info PED-EM-L
The URL for the PED-EM-L Web Page is:
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